POST SLEEVE GASTRECTOMY FISTULA: EXPERIMENTAL MODEL IN PIGS: POST SLEEVE GASTRECTOMY FISTULA: EXPERIMENTAL MODEL

Irami Araujo-Filho; Amália Cinthia  Meneses do Rêgo; Thais Cristina  Loyola da Silva; Francisco Irochima  Pinheiro

doi:10.20398/jscr.v14i1.33016

Authors

Irami Araujo-Filho UFRN
Prof. Dr. Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil;Full Professor of the Graduate Program in Biotechnology, Potiguar University (UnP) – Natal/RN - Brazil https://orcid.org/0000-0002-0575-3752
Ms. Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil https://orcid.org/0000-0003-1605-9923
Prof. Dr. Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil https://orcid.org/0000-0001-8879-3997

DOI:

https://doi.org/10.20398/jscr.v14i1.33016

Keywords:

Bariatric Surgery, Gastrectomy, Postoperative Complications, Fistula, Experimental Animal Model, Swine

Abstract

Introduction: Bariatric surgery is considered the primary treatment against severe obesity, as it is effective in sustained weight loss and reduces the prevalence of associated comorbidities. However, bariatric surgery is not free of complications observed at various postoperative stages, including fistulas. Purpose: To describe the creation of an experimental model of a gastric fistula after the performance of Sleeve Gastrectomy (SG) in pigs. Methods: Sleeve gastrectomy was performed in pigs, using tubes for postoperative fistula induction, following the ethical principles of animal experimentation. Results: After an observation period of 21 days, it was possible to confirm the formation of the fistulous tract. None of the animals died. Conclusion: The experimental model of post-Sleeve Gastrectomy fistula in pigs is efficient, effective, and reproducible and can be used in future studies to test new diagnostic methods and innovations in the therapeutic management of postoperative fistulas.

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Author Biographies

Prof. Dr. , Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil;Full Professor of the Graduate Program in Biotechnology, Potiguar University (UnP) – Natal/RN - Brazil

¹Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil; ORCID: https://orcid.org/0000-0002-0575-3752; Full Professor of the Graduate Program in Biotechnology, Potiguar University (UnP) – Natal/RN - Brazil. E-mail: regoamalia@gmail.com;

Ms., Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil

Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil. ORCID: https://orcid.org/0000-0003-1605-9923; E-mail: thais.loyola@liga.org.br;

Prof. Dr. , Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil

³Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal/RN – Brazil. ORCID: https://orcid.org/0000-0001-8879-3997; E-mail: irochima@gmail.com;

POST SLEEVE GASTRECTOMY FISTULA: EXPERIMENTAL MODEL IN PIGS