RELATIONSHIP INTESTINE AND CENTRAL NERVOUS SYSTEM: THE IMPORTANCE OF THE INTESTINAL MICROBIOME

A IMPORTÂNCIA DO MICROBIOMA INTESTINAL

Authors

DOI:

https://doi.org/10.21680/1984-3879.2024v24n1ID33359

Keywords:

Distúrbios neuropsiquiátricos, Eixo cérebro-intestino, Distúrbios neurodegenerativos.

Abstract

The intestine is very important in the food digestion and in its extension there are several species of microorganisms that belongs to the intestinal microbiome. The research aimed to determine the importance that food and the intestinal microbiome employs on the nervous system. A qualitative and retrospective bibliographical review was carried out, using scientific articles and books published in the databases: Google academic, Scientific Electronic Library Online (SciELO) Minha Biblioteca and Biblioteca Virtual em Saúde (BVS). Based on the bibliographic review, the predominance of the Bacteroidetes and Firmicutes phyla in the microbiome was noted, which are directly or indirectly responsible for the production of anti-inflammatory and pro-inflammatory responses; and that certain bacteria of these phyla are responsible for the production of some of the main neurotransmitters of the central nervous system. Based on the studies presented, we can report that the imbalance in the brain-intestine axis can lead to several disorders such as: obesity, Alzheimer's, anxiety and depression.

Downloads

Download data is not yet available.

References

BEZERRA, Ilana Nogueira et al. Consumo de alimentos fora do domicílio no Brasil. Revista de Saúde Pública, Rio de Janeiro, v. 47, n. 1, p. 200-211, fev. 2013. Disponível em: https://doi.org/10.1590/S0034-89102013000700006. Acesso em: 25 abr. 2023.

CONSÓRCIO DO PROJETO MICROBIOMA HUMANO (THE HUMAN MICROBIOME PROJECT CONSORTIUM). Structure, function and diversity of the healthy human microbiome. Nature, v. 486, n. 7402, p. 207-214, jun. 2012. Disponível em: http://dx.doi.org/10.1038/nature11234. Acesso em: 24 abr. 2023.

CUNHA, Andréa Mendonça Gusmão et al. Manual de farmácia 1: farmacologia. 2ª edição. ed. Salvador / Ba: Sanar Saúde, 2020. 268 p.

DINAN, Timothy G. et al. Collective unconscious: how gut microbes shape human behavior. Journal Of Psychiatric Research, v. 63, p. 1-9, abr. 2015. Disponível em: https://doi.org/10.1016/j.jpsychires.2015.02.021. Acesso em: 24 abr. 2023.

DURÇO, Guilherme Moreira; MAYNARD, Dayanne da Costa. OBESIDADE, FIRMICUTES E BACTEROIDETES: uma revisão da literatura. 2018. 17 f. TCC (Graduação) - Curso de Nutrição, Centro Universitário de Brasília – Uniceub, Brasília - Df, 2018. Disponível em: https://repositorio.uniceub.br/jspui/handle/prefix/13278. Acesso em: 24 abr. 2023.

MYLES, Ian A.. Fast food fever: reviewing the impacts of the western diet on immunity. Nutrition Journal, v. 13, n. 1, p. 1-17, 17 jun. 2014. Disponível em: https://doi.org/10.1186/1475-2891-13-61. Acesso em: 25 abr. 2023.

MORAES, Ana Carolina Franco de et al. Microbiota intestinal e risco cardiometabólico: mecanismos e modulação dietética. Arquivos Brasileiros de Endocrinologia & Metabologia, v. 58, n. 4, p. 317-327, jun. 2014. Disponível em: https://doi.org/10.1590/0004-2730000002940. Acesso em: 24 abr. 2023.

RIBEIRO, Izabela Martina Ramos; ANTUNES, Vagner Roberto. Vias Integrativas do Sistema Nervoso Autônomo no Controle do Trato Gastrointestinal. Sistema Digestório: Integração Básico-Clínica, São Paulo, p. 671-682, nov. 2016. Disponível em: http://dx.doi.org/10.5151/9788580391893-24. Acesso em: 25 abr. 2023.

SEZINI, Angela Maria; GIL, Carolina Swinwerd Guimarães do Coutto. Nutrientes e Depressão. Vita Et Sanitas, Trindade-Go, v. 8, n. 1, p. 39-57, 2014. Disponível em: http://fug.edu.br/revistas/index.php/VitaetSanitas/article/view/29/21. Acesso em: 25 abr. 2023.

SILBERNAGL, Stefan; LANG, Florian. Fisiopatologia. 2. ed. Porto Alegre: Artmed, 2016. 433 p. Disponível em: https://integrada.minhabiblioteca.com.br/#/books/9788536325996. Acesso em: 25 abr. 2023.

ZHU, Sibo et al. The progress of gut microbiome research related to brain disorders. Journal Of Neuroinflammation, v. 17, n. 25, p. 1-20, 17 jan. 2020. Disponível em: https://doi.org/10.1186/s12974-020-1705-z. Acesso em: 23 abr. 2023.

Published

15-05-2024

How to Cite

RODRIGUES, F.; ROSANY DE SALES SANTIAGO, P. .; FELIPE CHAVES CARVALHO, L. RELATIONSHIP INTESTINE AND CENTRAL NERVOUS SYSTEM: THE IMPORTANCE OF THE INTESTINAL MICROBIOME: A IMPORTÂNCIA DO MICROBIOMA INTESTINAL. Saberes: Interdisciplinary Journal of Philosophy and Education, [S. l.], v. 24, n. 1, p. AR12, 2024. DOI: 10.21680/1984-3879.2024v24n1ID33359. Disponível em: https://periodicos.ufrn.br/saberes/article/view/33359. Acesso em: 22 jul. 2024.